Protein Data Bank (PDB)

Here I am once again....

Today I am going to talk about the great Protein Data Bank...shortform PDB..

Definition: The Protein Data Bank (PDB) is a repository for the 3-D structural data of large biological molecules, such as proteins and nucleic acid.

This PDB is a member of the worldwide Protein Data Bank(wwPDB).

PDB has its special webpage which can be viewed by users to search for annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists. 

The PDB database is updated weekly (on Tuesday). As of Tuesday Oct !2, 2010 at 5pm PDT there are 68562 Structures

Click HERE to view the official webpage of PDB.

For today's assignment I have to talk about Crystal structure of Bacillus subtilis Lon-N terminal domain

To search for this structure at the PDB webpage, firsly we would have to write the word" lonA" at the search box, where it gives to different kinds of structure which are 3M65 and 3M6A..I choose the first structure to talk about which is 3M65..reacearch about this structure was done by the author Duman,R.E. and Lowe, J.Y.

Here is a picture of the structure whereby the structure is in the form of ribbon and color being temperature..

Primary citation about this lonA structure:
Lon ATP- dependent proteases are key components of the protein quality control systems of bacterial cell and eukaryotic organelles. Eubacterial Lon proteases contain a N- terminal domain an ATPase domain, and a protease domain all in one polypeptide chain. The N-terminal domain is thought to be involved in substrate recognition, the ATPase domain in substrate unfolding and translocation into the protease chamber, and the protease domain in the hydrolysisof polypeptides into small peptide fragments.

Molecular structure:

Classification	Structure Weight	Molecule
Hydrolase	48027.40	ATP-dependent protease La 1

Thats all from me about Bacillus subtilis...
sigining out for now.......